# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "networkABC" in publications use:' type: software license: GPL-3.0-only title: 'networkABC: Network Reverse Engineering with Approximate Bayesian Computation' version: 0.8-1 identifiers: - type: doi value: 10.32614/CRAN.package.networkABC - type: url value: https://github.com/fbertran/networkABC/ abstract: We developed an inference tool based on approximate Bayesian computation to decipher network data and assess the strength of the inferred links between network's actors. It is a new multi-level approximate Bayesian computation (ABC) approach. At the first level, the method captures the global properties of the network, such as a scale-free structure and clustering coefficients, whereas the second level is targeted to capture local properties, including the probability of each couple of genes being linked. Up to now, Approximate Bayesian Computation (ABC) algorithms have been scarcely used in that setting and, due to the computational overhead, their application was limited to a small number of genes. On the contrary, our algorithm was made to cope with that issue and has low computational cost. It can be used, for instance, for elucidating gene regulatory network, which is an important step towards understanding the normal cell physiology and complex pathological phenotype. Reverse-engineering consists in using gene expressions over time or over different experimental conditions to discover the structure of the gene network in a targeted cellular process. The fact that gene expression data are usually noisy, highly correlated, and have high dimensionality explains the need for specific statistical methods to reverse engineer the underlying network. authors: - family-names: Bertrand given-names: Frederic email: frederic.bertrand@utt.fr orcid: https://orcid.org/0000-0002-0837-8281 - family-names: Maumy-Bertrand given-names: Myriam email: myriam.maumy@utt.fr orcid: https://orcid.org/0000-0002-4615-1512 preferred-citation: type: manual title: Network Reverse Engineering with Approximate Bayesian Computation authors: - family-names: Bertrand given-names: F. - family-names: Maumy-Bertrand given-names: M. publisher: name: manual year: '2022' notes: R package version 0.8-1 url: https://fbertran.github.io/homepage/ repository: https://fbertran.r-universe.dev repository-code: https://github.com/fbertran/networkABC/issues/ commit: 3cd3adb483971d67a21f533ae9a3640748039541 url: https://fbertran.github.io/networkABC/ date-released: '2022-10-18' contact: - family-names: Bertrand given-names: Frederic email: frederic.bertrand@utt.fr orcid: https://orcid.org/0000-0002-0837-8281 references: - type: article title: Network Reverse Engineering with Approximate Bayesian Computation authors: - family-names: Maumy given-names: M. - family-names: Bertrand given-names: F. journal: user! 2021 year: '2021' notes: Zurich url: https://user2021.r-project.org/participation/technical_notes/t164/technote/